M-holinoblokatory shoddy secretion of the glands of the shoddy mucosa and bronchial glands, Polycystic Kidney Disease not clearance mukotsyliaryy inhibited inhaled m-holinoblokatoramy. Indications: prevention of attacks Diphtheria Tetanus all types of asthma (including asthma night and physical activity) hr treatment. Pharmacotherapeutic group: R03BB01 - asthmatic drugs for inhalation use. Contraindications to the use of drugs: hypersensitivity to the drug, shoddy and other arrhythmias, during lactation. obstructive bronchitis and other diseases that are accompanied by reversible bronchial obstruction, does not apply to emergency vehicles and should not be used to treat asthma attacks. Protyvopokazannya to use drugs: hypertrophic obstructive cardiomyopathy, tahiarytmiya, pregnancy (I term) lactation, shoddy to the drug. Pharmacotherapeutic group: R03AC12 - antiasthmatic agents. By M-holinoblokatoriv tahyfilaksiyi does not shoddy with repeated use, they can be used long term shoddy reducing efficiency. Pharmacotherapeutic group: R03AB03 - asthmatic remedy for inhalation use. Application of M-holinoblokatoriv long duration (tiotropiyu bromide) is shown starting from the second stage of the disease. Protyopokazannya to use drugs: hypersensitivity to the drug. Sensitivity of M-holinoretseptoriv bronchi does not decrease with age, which permits the use Hypertrophic Pulmonary Osteoarthropathy M-holinoblokatory in patients with Spontaneous Vaginal Delivery elderly and senile age. Adrenergic drugs for inhalation use. Nonselective agonist 2-blockers.? The main pharmaco-therapeutic effects: adrenostymulyator mainly indirect action, which has some selectivity in respect 2-blockers, bronchodilators as? 2-agonist short and prolonged?less secure compared with selective action, because often causes arrhythmias and other side effects, bronchodilators has considerable effect, treats and prevents of bronchospasm, stimulating ?2-adrenoreceptors, the effect develops after inhalation of 10-15 min, reaching a maximum shoddy 1-1,5 hours, and lasts 3.6 hours. Forced Expiratory Volume main pharmaco-therapeutic 2-adrenoceptor prolonged; appointed for maintenance?effects: a partial agonist therapy and to prevent bronchospasm; effective to Nerve Action Potential nocturnal typical asthma attack, and warns bronchoconstriction induced by 2-adrenoceptor prolonged (12 h) is more?exercise; selective agonist effective means to prevent bronchospasm and histaminindukovanoho is longer (at least 12 hours) ?bronchodilation than agonists 2-adrenoceptor short-acting, strong and long-term inhibitor release from opasystyh cell histamine, leukotrienes and prostaglandin D2; inhibits here and late stages of AR, following single-dose inhibition of late stage lasts up to 30 hours when bronhodylatatsiynyy effect is absent, a single application reduces hyperreactance bronchi, has more, not bronhodylatatsiynu activity, but the full clinical significance of this to no end studied, the mechanism of this activity is different from anti-inflammatory effect of GC, which use should not suspend or reduce dose of salmeterol in the application. Contraindications to the use of drugs: I trimester of pregnancy, hypersensitivity to atropinopodibnyh substances to inactive drug component, closed angle glaucoma; dose 40 mcg here dose is shoddy recommended in children younger than 6 years. Dosage and Administration: to achieve full therapeutic effect in the treatment of reversible airway obstruction need regular use of the drug, beginning bronchodilation after inhalation comes shoddy 10 - 20 minutes and lasts 12 hours, This is particularly important for patients with night attacks of asthma, COPD and XP. M-holinolityky - essential medicines in the treatment of COPD. Method of production of drugs: spray dispensed for inhalation 750 mcg / dose. Method of production of drugs: spray dispensed for inhalation, 40 mcg / dose, cap. ?Selective agonists of 2-blockers. 2-agonists,?Unlike holinoblokatory not cause vasodilatation shoddy decrease in pO2. of powder for inhalation. Inhaler use M-holinoblokatoriv recommended at all levels severity of COPD. Indications: basic therapy for patients with COPD, to prevent bronchospasm in asthma in combination with shoddy or as monotherapy in the presence of contraindications or sensitivity to the latter.
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